Tumor necrosis factor and viral myocarditis: the fine line between innate and inappropriate immune responses in the heart.
نویسنده
چکیده
Inappropriate Immune Responses in the Heart Tumor Necrosis Factor and Viral Myocarditis: The Fine Line Between Innate and Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.103.5.626 2001;103:626-629 Circulation. http://circ.ahajournals.org/content/103/5/626 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Killer Cell Immunoglobulin-Like Receptors Influence the Innate and Adaptive Immune Responses
Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the unhealthy cells from the healthy ones through an array of cell-surface receptors. Human NK cells use inhibi...
متن کاملEffect of Aloe Vera Herbal Extract on Innate Immunity in Balb/c Mice Against Candida Albicans
Background: Based on the reports, Aloe vera extract, a herbal medicine, has antimicrobial and anti-inflammatory effects. Also, this medicinal plant has considerable effects on innate immunity through cytokine secretion which resist fungal infections such as Candida albicans. Moreover, Aloe vera is considered as immunomodulatory agent and regulate inflammatory responses. Materials and Methods: I...
متن کاملInnate immunity and cardiac preconditioning: a putative intrinsic cardioprotective program.
Ischemic preconditioning is thought to evoke cell survival programs in the heart in large part via the activation of G(I)-protein coupled receptor signal transduction pathways. However, the identification and characterization of G(I)-protein coupled receptor independent pathways would enable researchers to pursue novel cellular events that could direct or promote preconditioning. In this regard...
متن کاملT regulatory cells: sentinels against autoimmune heart disease.
Myocarditis is an acute inflammatory disease of the heart and a precursor of dilated cardiomyopathy.1–8 Dilated cardiomyopathy is a more chronic disease which is characterized by ventricular hypertrophy and which may be a direct result of myocarditis and lead to heart failure.1–3,9 Myocarditis is often characterized by a cellular infiltrate, and if inflammation of the myocardium does not resolv...
متن کاملImpact of Metformin and Pioglitazone on Serum Level of Tumor Necrosis Factor-Alpha and Lipid Profiles during Implantation Window in Diabetic Rats
Objective Objectives: The present study was designed to evaluate the serum lipid profile and Tumor Necrosis Factor alpha (TNF-ɑ) level in diabetic rats at the time of implantation. Type 2 diabetes mellitus (T2DM) could affect various systems, including innate immune system and causes chronic low-grade inflammation which increases the level of TNF-ɑ. Furthermore, T2DM is often accompanied by imp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation
دوره 103 5 شماره
صفحات -
تاریخ انتشار 2001